In 2006, Andrew Fire and Craig Mello shared the Nobel Prize in Physiology or Medicine for their discovery of RNA interference (RNAi), which they published in 1998. Since then, the potential of a technology capable of silencing disease-causing genes has been a very attractive proposition.
As a result of the One Big Beautiful Bill Act, the lifetime exclusion for gifts and estates will increase permanently to $15 million next year with annual inflation adjustments to follow.
Doug Drabik discusses fixed income market conditions and offers insight for bond investors.
Fixed Income Portfolio Managers Brent Olson and Tom Ross consider current credit spread levels and offer reasons why they could remain rangebound for some time.
Markets surged to record highs in 3Q 2025 as the Fed’s first rate cut reignited optimism, with AI-driven market growth and broader participation leading gains, but a cooling labor market and fiscal uncertainty set the tone for a more selective, year-end investment positioning in 4Q
Labor markets are not keeping pace with young adult populations.
American companies continue to buy back their shares at a record pace in 2025. This has not only padded balance sheets but it’s helped drive the stock market rally that’s persisted since the April 8 trough.
When bear market losses occur, headlines talk in percentages: “The market dropped 20 %.” Investors nod. A 20 % decline sounds manageable, historical, and expected.
In big news for the energy infrastructure space, Targa Resources Corp. (TRGP) has announced significant new investments in its Permian Basin operations. The announcement includes a new natural gas liquids (NGL) pipeline and incremental natural gas infrastructure.
On this episode of the “ETF of the Week” podcast, VettaFi’s Head of Research, Todd Rosenbluth, discusses the Calamos Laddered S&P 500 Structured Alt Protection ETF (CPSL) with Chuck Jaffe of Money Life. The pair discusses several topics related to the fund to give investors a deeper understanding of the ETF.
Amrita Nandakumar, President of Vident Asset Management, explains the role of an ETF subadvisor and shares her unique perspective on ETF product development, the forthcoming multi-share class structure, and the potential impact of a “lighter touch” regulatory environment. Roxanna Islam, Head of Sector & Industry Research at VettaFi, also weighs in on the multi-share class structure, and discusses the latest developments in crypto ETFs and the stellar performance of gold and silver miner ETFs.
Whether you're seeking smoother client outcomes, more adaptive portfolios, or just more control, this conversation is built for you. Join Swan Global Investments and VettaFi for a deep dive into the value and utilization of active options strategies.
Join the experts at SS&C ALPS Advisors and CoreCommodity Management for an in-depth educational webcast exploring the natural resource equities space.
Chasing sends a clear message to your prospects, mainly you care more about closing the deal than solving their problem. There is an alternative, and a simple one at that. Stop following up and start focusing on creating trust.focusing on creating trust.
If you are searching for professional retirement and financial guidance, the most important thing is working with professional people who understand your needs and can help you in achieving your specific goals. How might you determine compatibility?
Inflation is a quiet seeping in the background that you may not notice today. Yet over years it can drain value from your retirement reservoir. The fix doesn’t require a full remodel, just regular maintenance. What kind of maintenance does it take to prevent inflation leakage? Here are a few suggestions.
Many investors have turned to MLPs over the years for their income, which makes the outlook for distributions a perennial focus for investors. With MLP yields currently elevated relative to long-term averages and a flattish near-term outlook for U.S. energy production, the distribution outlook is particularly topical.
A trio of money managers want to sell exchange-traded funds that amp up swings in Tesla, Bitcoin and other assets to a rarely seen degree, setting the stage for another test of regulators’ tolerance for ultra-risky offerings.
The extra yield investors demand to own dollar bonds of emerging market sovereigns rather than US Treasuries has shrunk to the least in seven years — and the rally is set to run further.
Gold steadied as the dollar edged higher, cooling a record-breaking rally that’s been further fueled by the US government shutdown and the political crisis in France.
Investors are excited about OpenAI’s expansion driving big gains in technology stocks, but a rising number of Wall Street pros fear that the wild pops that add tens of billions of dollars in value in mere minutes are signaling an unhealthy market reminiscent of the dot-com era.
Rising investor appetite for digital infrastructure, energy and transportation assets boosted fundraising for Manulife Investment Management, which closed its largest-ever infrastructure fund with $5.5 billion.
Three things to watch this month from Franklin Templeton Emerging Markets Equity: China's Golden Week, tariffs on India and the likelihood of a year-end market rally.
We believe corporate America will follow up an outstanding second quarter earnings season with another good one in the third quarter.
With equity markets reaching new heights, the market’s expectation that the US Federal Reserve will cut rates to head off a labor-market slowdown is itself creating a policy challenge for the central bank.
Emerging markets investing has had an overall positive year in 2025. Entering the year, with many U.S. investors underweight foreign equities, some market watchers anticipated big opportunities abroad.
With the global economy proving more resilient than expected, we upgrade equities to overweight.
No one, that we know of, is saying Artificial Intelligence (AI) isn’t an amazing new technology that will have an important impact on life, investing, and the economy.
Markets digested a quiet jobs Friday without the official payrolls report, but the signal from the other indicators was clear enough: the labor market is slowing at the margin but not falling off a cliff.
The office real estate sector is working through a difficult cycle.
Defined contribution (DC) plans form the backbone of retirement security for millions of Americans. And while stocks often steal the spotlight for their growth potential, bonds play a crucial role in managing risk, providing diversification, and delivering reliable income—especially as participants approach retirement.
Like AI stocks, precious metals look overbought; but unlike AI stocks, they’re structurally underinvested. As such, I believe they deserve another look.
It will depend on how long the budget stalemate drags out, but from a historical perspective, the impact of government shutdowns has been relatively short-lived and contained.
Over the next decade, almost every rich country will have to face fiscal reality. All have expanded their welfare state to serve not only the needy but also the middle class, with expensive pensions, health care and worker benefits.
Join the experts at Allspring Global Investments as they cover how investors can position their bond portfolio in today’s unusual environment.
Some political commentators believe Stephen Miran is a pawn of President Trump, aiming solely to lower interest rates, regardless of whether such action is justified. But, regardless of your political views, set aside your own perspectives for a moment and consider Miran’s views on the economy and monetary policy.
Investors and asset managers are often looking to markets to see if there are any early warning signs before a market blows up. Some investors swear by metrics such as credit expansion, IPO mania, or even meme stocks as early evidence that something is about to go wrong.
In this article, I will discuss the process financial advisors can follow to help their clients determine how much they should initially set aside for LTC and how to periodically monitor whether the amount their clients have set aside (the reserve) continues to be sufficient in the future.
If speaking of “win-win solutions” is a naïve surrender to Chinese propaganda, then virtually everything that isn’t an expression of bellicosity toward China also is. But of course, those like Pottinger and Fishman who believe that bellicosity toward China is the only way to defend the U.S. against it are falling into the trap of the “security dilemma.”
Electricity demand is on the rise globally thanks to electrification, adoption of electric vehicles, wider use of air conditioning, and the rise of AI-related data centers.
Boeing Co. is guiding suppliers that 737 Max output could reach a 42-jet monthly tempo as soon as this month, according to people familiar with its plans, highlighting growing optimism at the planemaker as it works to win approval for the move from US regulators.
The stock market as we know it is on the brink of a transformation.
OpenAI may not be publicly traded, but the world’s most valuable startup is increasingly making waves in the stock market.
Advanced Micro Devices Inc. shares surged after the chipmaker signed a deal with OpenAI for AI infrastructure that could generate tens of billions of dollars in new revenue.
Over the past three years, the economic conversation has been a “promised recession.” If you read the headlines, tracked economist surveys, or even listened to Wall Street strategists, you would have assumed a downturn was imminent. And yet, here we are, late into 2025, and the U.S. economy is still standing.
Government shutdowns are not unprecedented. Although some volatility is possible, historically, there has been no clear relationship between U.S. government shutdowns and market returns.
In the absence of primary government indicators, policymakers and investors alike must turn to private sector releases to find clarity. These secondary reports paint a picture of a cooling labor market and an increasingly cautious consumer.
In this article, Russ Koesterich discusses how September, typically a month that exhibits seasonal market weakness, is showing surprising strength.
Within the emerging markets story in 2025 is a potentially even more intriguing subplot: the strong performance of Africa equities.
Vanguard announced the debut of a new low-cost, emerging markets (EM) exchange-traded fund (ETF) — the Vanguard Emerging Markets ex-China ETF (VEXC). EM assets have been garnering increased investor attention this year and could see additional interest with the prospect of more interest rate cuts to come.
